Planning Guide

Creating Learner-Focused
Schools

* Madison-Oneida BOCES- This document may not be reproduced in any form without the expressed written consent of the District Superintendent or his designee.

 

LU Title: DNA, Protein Synthesis and Mutations

Author(s): Rebecca Buckingham

Grade Level: Tenth Grade

School Address: Lisbon Central School, 6866 Co. Route 10, Lisbon, NY 13658

Subject Area: Biology

School Phone/Fax: (315)393-4951/7666

 

CONTENT KNOWLEDGE

Declarative

Procedural

  • The chemical composition and role of DNA
  • Simulating DNA replication
  • Comparing DNA and RNA with each other
  • Simulating DNA and RNA working together to synthesis protein
  • Comparing the three types of RNA with each other
 
  • Gene chromosome theory
 
  • How the environment influences our appearance
 
  • How mutations influence genetic codes
 

 

ESSENTIAL QUESTIONS

 

INITIATING ACTIVITY

What is Cheyrnobl? Ask for ideas from the students. Then show a video clip on Cherynobyl that depicts what is and what were the results.

 

Connection to State Learning Standards

Content Area: Biology/Genetics

Level: Tenth Grade

Benchmarks: Key Idea - 2 - Organisms inherit genetic information in a variety of way that result in continuity of structure and function between parents and offspring.

 

Benchmarks: Listening and Reading - Students can acquire and analytically use information from a wide variety of sources for many purposes.

 

Standard: MST - Science - Standard 4 - Students will understand and apply scientific concepts, principles, and theories pertaining to the physical setting and living environment and recognize the historical development of ideas in science.

 

Standard: ELA - Standard 1 - Language for information and understanding.

 

Learning Experiences

Declarative Knowledge

What declarative knowledge should e in the process of acquiring & integrating? As a result of the unit, the student will know or understand…

What experiences or activities will be used to help students acquire & integrate this knowledge?

What strategies will be used to help students construct meaning, organize and/or store the knowledge?

Describe what will be done.

 The chemical composition and role of DNA

Comparing DNA and RNA chemical composition and roles

Comparing the three types of RNA with each other

Gene chromosome theory

How the environment influences our appearance

How mutations influence genetic codes

CD ROM of DNA composition called "Life Story" (Clearvue) students use disks to discover what DNA is and who contributed to its discovery

Multimedia CD ROM "From DNA to Protein" (Cyber Ed Inc. Products) laser disk player lecture with discussion

CD ROM tutorial "Glencoe Interactive Life Science" (Glencoe Textbook publisher) with discussion on their role with protein synthesis

Lecture

Discussion of blond hair in winter in NNY versus summer, if boards are on grass what color is the grass, etc.

Worksheet in pairs, do protein synthesis, then change one base by addition, deletion, or substitution and have pairs redo protein synthesis

Lecture gene versus chromosomal mutation

 C - KWL; O - graphic organizer; concept map

C - three minute pause strategy; O - comparison graphic organizer

C - reciprocal teaching strategy; O - graphic organizer; concept map

C - bookends before lecture; O - flow chart

C - word splash; O - web diagram

C - paired partners activity; O - graphic organizer to show mutation types; M - coop group posters using color and verbally explaining their meaning to the class

Students do a KWL of DNA. Students then work in small groups using the computer program "Life Story" from Clearvue. They take notes on what new information that they learn or what they find out interesting. We use these notes to do the "L" and organize the information into a concept map.

We do a three minute pause to review information from DNA and then student groups use the CD program to find out the connection between DNA and RNA. They are given a comparison graphic organizer to complete.

Students work in small groups to discover how protein synthesis involves the three types of RNA. They complete a graphic organizer to compare and contrast the three types.

Students discuss relationship of genes, DNA and chromosomes. Lecture is given, then they complete a flow chart with their partner to show this relationship.

Terms of phenotype, genotype, and environment are on a word splash for students to consider. Notes given on a web.

Students complete a worksheet on pairs that show effects of various gene mutations. Lecture is given on a variety of chromosomal mutations. Graphic organizers are used to organize notes. Cooperative groups then work on an activity to compare a gene mutation with a chromosomal mutation.

 

Learning Experiences

Procedural Knowledge

What procedural knowledge will students be in the process of acquiring & integrating? As a result of this unit, students will be able to:

What will be done to help students construct models, shape & internalize the knowledge?

Describe what will be done.

 Simulating DNA replication

Simulating DNA and RNA working together to synthesis protein

Teacher will show a video clip from the laser disk on DNA replication. Teacher will model using a think aloud, then model again, but this time ask students questions about the process, then give students an example to do as a think/pair/share. Think/pair/share will de done several times as needed. Think/pair/share flow chart of procedure.

Think aloud and modeling followed with think/pair/share for individual understanding. Students work in collaborative pairs to develop a flow chart of the process.

Think aloud and modeling followed with think/pair/share for individual understanding.

Teacher assigns roles to students of either DNA, one type of RNA, or an amino acid. Students then are led through a play about protein synthesis. Students then become directors of the play and assign new roles. Students use cards with their role for their "costume".

 

Learning Experiences

Extending and Refining

What knowledge will students be extending and refining? Specifically, they will be extending and refining their understanding of…

What reasoning process will they be using?

Describe what will be done.

 Gene Chromosome theory

Protein synthesis

Comparing

  • Classifying

Inductive Reasoning

Deductive Reasoning

Error Analysis

Analyzing Perspectives

  • Constructing Support
  • Abstracting

Other:

Induction: The teacher will prepare materials for this activity. Students will simulate electrophoresis of DNA strands that have been cut with enzymes to determine relationships of individuals. Students will be using DNA strands from a mother, husband, child, and child's supposed biological father to determine the child's paternity (and child support payments). Students will write a report of their findings to the lab chairman.

Error Analysis: Students will analyze the results of a report from a murder scene of DNA results that was developed by the teacher. Students will analyze a sequence of amino acids and the DNA strand that they were formed from to see if there were any errors and describe these errors and how to correct them. The students then write a report to the head forensic specialist to confirm his/her findings.

 

Planning Guide

 

Unit:

 

Step 1

Step 2

Step 3

What knowledge will students be using meaningfully? Specifically, they will be demonstrating their understanding of and ability to...........

What reasoning process will they be using?

Describe student's products and performances and the criteria for evaluation.

 

[ ] Decision Making
(selecting from seemingly equal alternatives or examining the decisions of others)
[ ] Problem Solving
(seeking to achieve a goal by overcoming constraints or limiting conditions)
[ ] Invention
(creating something to meet a need or improve on a situation)
[ ] Experimental Inquiry
(generating an explanation for a phenomenon and testing the explanation)
[ ] Investigation
(resolving confusions or contradictions related to a historical event, a hypothetical past or future event, or to the defining characteristics of something)
[ ] Systems Analysis
(analyzing the parts of a system and how they interact)
[ ] Other:

Products/Performances

Criteria for evaluation

Rubric:

Key Questions:

What are the key elements, traits, or dimensions that will be evaluated?

Are the identified elements of equal importance or will they be weighed differently?

Element #1

Element #2

Element #3

Element #4

Elements


Scale

 Identifies known information

Identifies problems

Provides and supports a position

Uses proper grammar, punctuation and spelling, cites work properly

Weights

 

 

 

 

4

Information is correct and covers topic completely

Information is correct and shows great insight into the problem(s)

Provides a clear position with strong support

No errors in grammar, spelling, punctuation, or citing of work

3

Information is correct, but lacks some important aspects of the topic

Information is correct and shows some insight into the problem(s)

Provides a clear position with weak support

Few errors in grammar, spelling, punctuation, or citing of work

2

Information is mainly correct, but lacks many important aspects of the topic

Information is correct, but shows little insight into the problem(s)

Position is unclear so support is hazy

Many errors in grammar, spelling, punctuation, or citing of work

1

Information is mainly incorrect

No problems are identified

No position is given or there is no support for the position

Numerous errors in grammar, spelling, punctuation, or citing of work

 NOTE: Rubric or other performance assessment instruments may be used.

 

Have You Considered These Yet?

Learn to Learn Skills:

Students use outside resources to obtain information.

Students practice notetaking skills to share for class notes.

Assessment Modifications:

Students who have problems with the writing tasks are given opportunities to verbally explain the information.

Unit Schedule/Time Plan:

3-4 weeks

Written Overview:

Students are led through a series of computer tutorials and lectures to build their understanding of DNA replication and its role in protein synthesis and mutation. This prepares the class for discussion of genetic engineering and its role in creating an "improved" population. This also sets the stage for discussion of evolution.